Suppose one wishes to learn more about (say) nonlinear kinetics with PREDPP. The term "nonlinear" is listed among the miscellaneous topics in the second section:ĪDVAN6 ADVAN8 ADVAN9 Michaelis Menten example The help and html directories of the NONMEM 7.4 distribution media contain essentially the same con- tent as this printed guide, enabling the contents of this guide to be searched and displayed on-line.
Some of the examples are drawn from other NONMEM guides and sources, and some are new to this guide.Īll sections are arranged in alphabetic order. If none are selected to appear, then the default option, listed first and indicated in boldface (if there is an option so indicated), is understood to apply. If they surround a group of options, a vertical line is used to separate these options in the description, and at most one of the options may be selected to actually appear in the record. The reserved words and miscellaneous topics appear in the left column of their respective sections, with titles of corresponding and relevant detailed descriptions and examples in the right column. The detailed descriptions provide brief summaries of the subject matter and are not intended to replace the other NON- MEM guides, which should be consulted if more information is needed.ĭescriptions of NM-TRAN control records have a special syntax that is described fully in Guide IV, sec- tion III.A. Please note that square brackets are used to surround an option or group of options, none of which need actually appear in the record.
Reserved Words Miscellaneous Topics Detailed Descriptions Examples This guide is intended to provide experienced users of the NONMEM system with a fast way to locate information on a given reserved word or topic. TNPRI examples EX-150 Transit Compartment Examples Repetition 1 example EX-127 Repetition 2 example EX-130 Simulation 1 example EX-132 Simulation 2 example EX-134 Simulation 3 example EX-135 Stieltjes example EX-137 Stochastic Differential Equation examples EX-138 Superproblem 1 example EX-139 Superproblem 2 example EX-142 TDM example EX-144 Three compartment example EX-145 Time After Dose (TAD) Example Logistic regression example EX-93 Michaelis Menten example EX-94 Mixture model example EX-95 Model Time examples EX-96 Moving Area Under the Curve Example EX-98 Multiple dose example EX-102 Nonparametric example EX-104 NWPRI examples EX-106 Objective Function Value Individual example EX-110 Phenobarb example EX-112 PK PD sequential 1 example EX-113 PK PD sequential 2 example EX-114 PK PD simultaneous 1 example EX-115 PK PD simultaneous 2 example EX-116 PK PD simultaneous 3 example EX-117 PK PD simultaneous 4 example EX-118 Plasma urine example EX-119 RECORDS=ID Example Initial Steady State example EX-85 Interoccasion variability example EX-88 INTERPOLATION IN $DES Copyright by the Regents of the University of California 1996, 1998, 2006, 2009 Copyright by ICON plc 2011, 2012, 2013, 2014, 2015, 2016, 2017,2018,2019, 2020 All rights reserved ContentsĬCONTR example EX-51 Control3 example EX-53 Control4 example EX-54 Control5 example EX-55 Control6 example EX-56 Control7 example EX-57 Data average example EX-58 Enterhepatic circulation examples EX-60 Examples Using MTIME to Model Periodic Discontinuities in $DESĮxogenous supplementation example EX-67 Expectation example EX-69 Finalization example ($PRED and $INFN)įinedata example EX-74 FOCE PARALLEL example EX-74 Ignore accept example EX-76 Infn interpolation example 1
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